Digestive Enzymes Market Expected to Reach $1.64 Billion by 2031—Allied Market Research

According to a new report published by Allied Market Research, titled, “Digestive Enzymes Market," The digestive enzymes market size was valued at $699.40 million in 2021, and is estimated to reach $1.64 billion by 2031, growing at a CAGR of 8.7% from 2022 to 2031. 

Digestive enzymes turn food taken into energy, which may be utilized by the body for various biological processes. Human bodies naturally produce both digestive and metabolic enzymes. Digestive enzymes are protein chemicals, which carry a vital energy factor needed for every chemical action and reaction that occurs in body. Digestive enzymes are secreted along the digestive tract to breakdown food into nutrients and waste. Most digestive enzymes are produced by pancreas. Liver, gallbladder, small intestine, stomach, and colon play pivotal roles in production of these enzymes. Digestive enzymes allow nutrients found in foods consumed to get absorbed into the blood stream and waste to be discarded. Some human digestive enzymes include lipase, protease, amylase, ptyalin, pepsin, and trypsin.

The digestive enzymes market share is expected to experience significant growth during the forecast period, owing to increase in prevalence of digestive problems, increase in unhealthy lifestyle by population, and rise in geriatric population. Moreover, surge in number of fitness centers and gymnasiums has also increased demand for dietary supplements, increase in awareness about GI health, and focus on preventive disease management are other digestive enzymes market trends. However, lack of knowledge about appropriate dosage amounts and presence of substitutes for digestive enzyme supplements are expected to hinder growth of the market. Conversely, development of customized digestive enzymes offer lucrative opportunities in digestive enzymes market growth.

Coronavirus (COVID-19) was discovered in late December in Hubei province of Wuhan city in China. The situation of COVID-19 has varied outcome when related to vaccinations. There is an emerging gap in the economic recovery between high-income and low and middle income countries. After the pandemic severely disrupted global trade, the world is witnessing a robust rebound, which is helping with the recovery in the year 2021. Trade contributes to speeding up economic recovery from the pandemic by providing sustained foreign demand for exports and ensuring the availability of imported intermediate products and services. The COVID-19 pandemic affected the digestive enzymes industry in a fairly negative way, like various other enzyme industries were affected. For instance, according to a review article by Wiley Online Library first published in June 2022, furin is a protease related to coronavirus cell entrance as it is responsible for cleavage of SARS-CoV-2 S protein in lung cells and primary human airway epithelial cells in a transmembrane serine protease-2 (TMPRSS2)-expression dependent manner. However, physiological consequences of inhibiting that enzyme are not known yet. Moreover, according to a study published in the American Journal of Gastroenterology in July 2020, as compared with non-severe COVID-19 patients, severe COVID-19 patients have higher levels of aspartate aminotransferase, alanine aminotransferase, and total bilirubin (TBL).

Overall, the COVID-19 pandemic had a fairly negative impact on the digestive enzymes industry owing to various restrictions imposed on the production and transport of products. However, this situation is expected to change during the forecast period after the pandemic is over.

By origin, the market is categorized into animals, microbial, and plants. The microbial segment dominated the market in 2021, and is anticipated to continue this trend during the forecast period owing to the trends such as rise in demand for microbial enzymes and surge in patient awareness toward effective & advanced technologies. In addition, the microbial segment is also expected to exhibit fastest growth during the forecast period owing to rise in number of cases of digestive disorders leading to the increase in demand of enzymes. Moreover, the launch of effective products, which are tested under clinical trials by the companies that ensure better therapeutic outcomes also contributes to the growth of the market.

By enzyme type, the market is segregated into carbohydrase, protease, lipase, and others. The carbohydrase segment accounted for majority of the market share in 2021, owing to rise in number of products available with carbohydrase enzyme and surge in geriatric population facing digestive problems. Moreover, the protease segment is expected to exhibit fastest growth rate, registering a CAGR of 9.4% from 2022 to 2030, owing to increase in demand for protease-based enzymes in the market.

By application, the market is segregated into prescription medicine, sports nutrition, and infant nutrition. The prescription medicine segment accounted for majority of the market share in 2021, owing to rise in prevalence of digestive disorders leading to rise in use of prescription medicines as supplemental aid and increase in focus on preventive disease management. Moreover, the sports nutrition segment is expected to exhibit fastest growth rate, registering a CAGR of 9.4% during the forecast period, owing to surge in number of fitness centers & gymnasium and increase in awareness about gastrointestinal (GI) health.

North America accounted for the highest revenue in the digestive enzyme market in 2021. The market growth in North America is supplemented by rapid advancements in enzyme products, increase in investments in research & development activities and rise in patient pool. However, Asia-Pacific is expected to emerge as the leading region by registering a CAGR of 9.9% during the forecast period. This is mainly attributed to rise in incidences of digestive disorders such as pancreatitis and pancreatic cancer leading the market growth.

KEY FINDINGS OF STUDY

• By origin, the microbial segment is expected to experience rapid growth in the market, and is projected to grow at a CAGR of 9.3% from 2022 to 2031.
• By enzyme type, the protease segment is projected to grow at a CAGR of 9.4% during the forecast period.
• By application, the sports nutrition segment is projected to grow at a CAGR of 9.4% during the forecast period.
• Region wise, Asia-Pacific is expected to experience growth at the highest rate, registering a CAGR of 9.9% during the forecast period.