Bone Void Fillers Market Size, Share, Competitive Landscape and Trend Analysis Report, by Type, by Form, by Application, by End User : Global Opportunity Analysis and Industry Forecast, 2021-2031

Bone Void Fillers Market Research, 2031

The global bone void fillers market size was valued at $3.2 billion in 2021, and is projected to reach $7.3 billion by 2031, growing at a CAGR of 8.5% from 2022 to 2031.Bone void is a complication caused due to failure of bone’s self-healing process. It creates cavity or gap in the bones. Bone voids are generated due to any bone defect from traumatic injury or due to surgical osseous. Bone void fillers are absorbable, biocompatible, bioactive, and osteoconductive in nature, which are used to fill bone gaps and cavities. They provide support and stability to bone structure. Different types of bone void fillers include demineralized bone matrix, calcium phosphate bone graft substitute, and collagen matrix bone graft substitute. They are available in different forms such as gel & putty, granules, paste, sponge, and liquid. Bone void fillers are used in various surgical procedure, such as spine fusion, bone fracture, pelvic surgery, and knee surgery.

The growth of the global bone void fillers market size is majorly driven by increase in prevalence of orthopedic diseases such as osteoarthritis, osteoporosis, scoliosis, bone tumor, and bone infection; increase in R&D activities in bone void fillers industry; rise in funding from private & government organizations for development of the healthcare sector and research centers; and surge in geriatric population. According to United Nations, in 2020, it was reported there were 727 million individuals aged 65 years or above, across the world. It was estimated that the number of aging people is projected to double to 1.5 billion by 2050. Moreover, according to the World Health Organization (WHO) in October 2021, it was reported that 1 in 6 people in the world will be aged 60 years or over by 2030. For instance, in 2020, Journal of EClinicalMedicine reported that approximately 22% of the population above the age of 40 years is diagnosed with knee osteoarthritis, globally. 

Furthermore, rise in number of product launch of bone void fillers is anticipated to fuel the bone void fillers market growth. For instance, in February 2022, Orthofix Medical Inc., medical equipment manufacturer for orthopedic and spine solutions, announced the launch of Opus BA, which is an synthetic bioactive bone graft and used for cervical and lumber spine surgery procedure. Moreover, in September 2021, Orthofix Medical Inc., announced the launch of Opus Mg Set, which is available in the form of synthetic magnesium-based bone void filler and used for orthopedic procedure. Opus Mg Set provides a procedure-specific solution for orthopedic fracture care and trauma applications by filling non-structural bony voids or gaps during surgery.

In addition, rise in number of orthopedic surgeries such as cervical and lumbar spine surgery procedure and increase in hip & knee replacements propel the growth of the bone void fillers market. For instance, according to report published by the American Joint Replacement Surgery (AJRS), approximately 2 million knee and hip replacement surgeries were performed in the U.S. in 2020.

Bone Void Fillers Market Segmentation

The bone void fillers market is segmented into  type, form, application, end user, and region. By type, the market is segregated into demineralized bone matrix, calcium phosphate bone graft substitute, collagen matrix, and others. The others segment include magnesium bone graft substitution and calcium sulfate bone void filler. on the basis of form, the market is fragmented into gel & putty, granules, and others. The others segment includes paste, powder, and liquid. Depending on application, the market is differentiated into spine fusion, bone fracture, and others. The others segment includes pelvic surgery and oral surgery. As per end user, the market is categorized into hospitals, specialty clinics, and others. The others include research centers and specialty clinics.

Region wise, the bone void fillers market share is analyzed across North America (the U.S., Canada, and Mexico), Europe (Germany, France, UK, Italy, Spain, and the rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea, and the rest of Asia-Pacific), and LAMEA (Brazil, Saudi Arabia, South Africa, and the rest of LAMEA).

Segment Review

On the basis of type, the market is classified into demineralized bone matrix, calcium phosphate bone graft substitute, collagen matrix, and others segment. The demineralized bone matrix segment dominated the market in 2021, and is expected to continue this trend during the forecast period, owing to increase in the use for dental implants and orthopedic surgery . On the other hand, calcium phosphate bone graft substitute segment is expected to witness considerable market growth during the forecast period, owing to increase in the use synthetic substitute such as polymer and ceramic in treatment of bone defects.

Depending on form, the market is segregated into gel & putty, granules, and others segment. The gel & putty segment exhibited the highest growth in 2021, and is  anticipated to lead in the coming future, owing to increase in the number of non-invasive and minimally invasive surgeries. However, the others segment is expected to witness considerable growth during the forecast period, owing to increase in the number of orthopedic surgeries which use bone void fillers material in the form of liquid, paste, sponge and powder.

By application, the market is fragmented into spine fusion, bone fracture, and others segment. The bone fracture was the prominent segment in 2021, and is expected to continue this trend during the forecast period, owing to increase in prevalence of osteoporosis, rise in geriatric population, and surge in cases of sport injuries & accidents. However, the spinal fusion segment is expected to witness considerable growth during the forecast period, owing to increase in the number of spine injury, and rise in number of spinal fusion procedure.

As per end user, the market is differentiated into hospital, specialty clinics, and others. The hospital segment  led the market in 2021, and is expected to continue this trend during the forecast period, owing to increase in initiatives taken by government to develop healthcare infrastructure, and rise in number of hospitals & clinics. On the other hand, specialty clinics segment is expected to witness considerable market growth during the forecast period, owing to rise in the awareness regarding specialty clinics.

North America accounted for a majority of the global bone void fillers market share in 2021, and is anticipated to remain dominant during the forecast period. This is attributed due to higher adoption of synthetic bone void fillers, large presence of bone void fillers industry, availability of well-developed healthcare infrastructure, and wide availability of bone void fillers. However, Asia-Pacific is anticipated to witness lucrative growth in the future, owing to increase in prevalence of orthopedic diseases, rise in awareness about the use of bone void fillers, surge in healthcare expenditure, and increase in geriatric population..

The key players operating in the global bone void fillers market include Arthrex Inc., Baxter Internation, DePuy Synthesis, Medtronic Plc., NuVasive Inc. Orthofix Medical Inc., Smith and Nephew Plc., Stryker Corporation, Wright Medical Group Inc., and Zimmer Biomet.

Key Benefits For Stakeholders

• This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the bone void fillers market analysis from 2021 to 2031 to identify the prevailing bone void fillers market opportunity.
• The market research is offered along with information related to key drivers, restraints, and opportunities.
• Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
• In-depth analysis of the bone void fillers market segmentation assists to determine the prevailing market opportunities.
• Major countries in each region are mapped according to their revenue contribution to the global market.
• Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
• The report includes the analysis of the regional as well as global bone void fillers market trends, key players, market segments, application areas, and market growth strategies.

  Bone Void Fillers Market Report Highlights

Aspects	Details
By Type	Demineralized bone matrix Calcium phosphate bone graft substitute Collagen Matrix Others
By Form	Gel and Putty Granules Others
By Application	Spine fusion Bone fracture Others
By End User	Hospital Specialty Clinics Others
By Region	North America  (U.S., Canada, Mexico) Europe  (Germany, France, U.K., Italy, Spain, Rest of Europe) Asia-Pacific  (China, Japan, India, Australia, South Korea, Rest of Asia-Pacific) LAMEA  (Brazil, Saudi Arabia, South Africa, Rest of LAMEA)
Key Market Players	NuVasive Inc, Stryker Corporation, Smith and Nephew plc, Wright Medical Group Inc, Arthrex Inc, Medtronic plc, Orthofix Medical Inc, Baxter International Inc., Zimmer Biomet, depuy synthes companies

Analyst Review

This section provides the insights of the top-level CXOs operating in the bone void fillers market. Bone void fillers are gaining high traction in the market, due to numerous product launches. For instance, in February 2019, Medtronic PLC, a medical device company, announced the launch of demineralized bone matrix (DBM), which is a bone void filler used in spine and orthopedic surgeries. Moreover, in January 2022, NuVasive Inc., a medical device company, announced approval from U.S Food and Drug Administration (FDA) for the product Attrax putty, which is a synthetic, bioactive, and osteoconductive bone void filler used in interbody fusions of the thoracolumbar spine. Furthermore, in July 2020, Baxter international, a medical equipment manufacturing company, announced the FDA clearance of Altrapore Shape bioactive bone graft, which is designed to enhance bone growth and help to achieve fusion. Thus, increase in the number of product approval fuels the growth of bone void fillers market.  

Author Name(s) : Linu Dash| Tanjeem Shaikh | Roshan Deshmukh

Related Tags

• Orthopedics
• Orthopedic Devices
• Biomaterials