Organoids and Spheroids Market Size, Share, Competitive Landscape and Trend Analysis Report, by Type, by Method, by End User : Global Opportunity Analysis and Industry Forecast, 2021-2031

Organoids and Spheroids Market Research, 2031

The global Organoids and Spheroids Market size was valued at $516.6 million in 2021 and is projected to reach $1.2 billion by 2031, growing at a CAGR of 8.5% from 2022 to 2031. Organoids are 3D-derived stem cell models, either from embryonic or adult stem cells. This type of organoid can exhibit self-regulation potential, phenotypic traits of the organ they are grown from, and physiological modeling of the environment through genomic alteration. Organoids are considered replication of complex organs such as the stomach, intestine, brain, kidney, lungs, and liver. Organoids are grown from stem cells of different sources, and these cells divide indefinitely and produce different types of cells. These structures resemble miniature organs, which range from the size of a hair width to five millimeters. Where as spheroids are well-designed cell aggregates used as engineered cancer models. They have the ability to boost the 3D construction of tumor growth to amplify tumor cell progression and to help reveal novel anti-cancer treatments. Tumor spheroids are able to reproduce the core properties of solid human tumors meticulously.

The Organoids and Spheroids Market trends are an increase in the adoption of personalized drugs, a rise in investments toward R&D activities, and a shift in preference toward organoid 3D cell cultures for cancer research. Furthermore, the rise in the prevalence of personalized medicines has increased the demand for organoids across the world. For instance, according to the National Center of Biotechnology Information in 2020, it was estimated that about 21 organoids clinical trials are ongoing in the world, and this number is estimated to increase in forthcoming years, owing to improvements in infrastructure and advancements in the scientific field. Furthermore, the increasing adoption of organoid technology for use in a range of applications, including genetic mutation, gene assessment, and tumor modeling is expected to drive the growth of the global organoids market. The assessment of different diseases by leveraging organoid technology is anticipated to remain one of the most prominent applications of organoids in the upcoming years.

In addition, the rise in technological advancement in 3D spheroids technologies in developing countries such as China, Japan, and India is expected to provide Organoids and Spheroids Market opportunity. However, the high cost of implementation hampers the Organoids and Spheroids Market growth.

The organoids and spheroids market is segmented on the basis of type, method, end user, and region. By type, it is bifurcated into organoids and spheroids. On the basis of method, it is fragmented into extracellular matrix scaffold method, spinning bioreactor method, hanging drop method, low adherent culture plate method, magnetic levitation method, and others. By end user, it is classified into biotechnology & pharmaceutical industries, academic & research institutes, and hospitals & diagnostics centers. Region-wise, it is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

Type Segment review

By type, Organoids and Spheroids Industry is segmented into organoids and spheroids. In 2021, the organoids segment accounted for the largest Organoids and Spheroids Market share. The dominance of this segment can be attributed to the rise in the adoption of organoids in various applications such as disease modeling, pathogenesis, drug screening, and regenerative medicine.

The spheroids segment is anticipated to grow at a significant rate during the forecast period owing to the rise in the adoption of spheroids in drug discovery, toxicology, and cancer research.

Method Segment Review

By the method, the organoids and spheroids market is segmented into extracellular matrix scaffold method, spinning bioreactor method, hanging drop method, low adherent culture plate method, magnetic levitation method, and others, the extracellular matrix scaffold method segment exhibited the highest growth in 2021, and is anticipated to lead during the forecast period. This is attributed to rise in the adoption of the extracellular matrix scaffold method, owing to various advantages such as cost-effectiveness and large production of spheroids and organoids in less time. The spinning bioreactor method segment is anticipated to grow at a significant rate during the forecast period owing to a rise in research and development activities for biopharmaceuticals and cancer drug research.

End User Segment Review

By end user, the biotechnology and pharmaceutical industries segment was the highest revenue contributor to the market owing to the increased use of organoids for biopharmaceuticals and cancer drug research. The academic & research institutes are expected to witness considerable market growth during the forecast period, owing to the increase in the adoption of organoids as a therapeutic tool for chronic disease, and the use of organoids in research & development.

Region Segment Review

Region-wise, Organoids and Spheroids Market analysis is done North America, Europe, Asia-Pacific, and LAMEA. The North America market was dominant, in terms of revenue among other regions in 2021, owing to the presence of several pharmaceutical and biotechnology companies that use organoid 3D culture technology in collaboration with research institutes and clinical laboratories for developing regenerative medicines and drug discovery & development across the world are the key factors which further propels the growth of the market in this region.

Asia-Pacific is estimated to grow at the fastest rate during the forecast period due to economic development and low operating costs. Moreover, the rise in focus on biopharmaceutical R&D, huge production of drugs, and surge in the prevalence of cancer propel the growth of the market in this region.

Key players that operate in the organoids and spheroid market are AMS Biotechnology Limited, ATCC, 3D Biotek LLC, 3Dnamics Inc., Cellesce Ltd., Corning Inc, DefiniGEN Ltd, Greiner AG, Hubrecht Organoid Technology, InSphero AG, Lonza, Merck KGaA, PeproTech Inc., Perkin Elmer Inc, Prellis Biologics, STEMCELL Technologies Inc., and Thermofisher Scientific Inc.

Key Benefits For Stakeholders

• This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the organoids and spheroids market analysis from 2021 to 2031 to identify the prevailing organoids and spheroids market opportunities.
• The market research is offered along with information related to key drivers, restraints, and opportunities.
• Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
• In-depth analysis of the organoids and spheroids market segmentation assists to determine the prevailing market opportunities.
• Major countries in each region are mapped according to their revenue contribution to the global market.
• Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
• The report includes the analysis of regional and global organoids and spheroids market trends, key players, market segments, application areas, and market growth strategies.

  Organoids and Spheroids Market Report Highlights

Aspects	Details
By Type	Organoids Type Neural Organoids Hepatic Organoids Intestinal Organoids Others Spheroids Type Multicellular Tumor spheroids Neurospheres Mammospheres Hepatospheres
By Method	Others Extracellular Matrix scaffold Method Spinning Boireactor method Hanging Drop method Low adherent Culture plate method Magnetic leviation Method
By End User	Biotechnology and Pharmaceutical Industry Academic and Research Institutes Hospitals and Diagnostic Centers
By Region	North America  (U.S., Canada, Mexico) Europe  (Germany, France, UK, Italy, Spain, Rest of Europe) Asia-Pacific  (Japan, China, Australia, India, South Korea, Rest Of Asia Pacific) LAMEA  (Brazil, Saudi Arabia, South Africa, Rest of LAMEA)
Key Market Players	Thermofisher Scientific Inc, DefiniGEN Ltd, Corning Inc, Greiner AG, Prellis Biologics, ATCC, Cellesce Ltd, Merck KGaA, Hubrecht Organoid Technology, InSphero AG, Lonza, 3Dnamics Inc, Perkin Elmer Inc, 3D Biotek LLC, PeproTech Inc., STEMCELL Technologies Inc

Analyst Review

This section provides opinions of top-level CXOs in the organoids and spheroid market. In accordance with several interviews conducted, the organoids and spheroid market is expected to witness significant growth in the future, owing to the rise in the adoption of spheroids technology for drug discovery, toxicology studies, and cancer research.

According to the perspectives of CXOs, the global organoids and spheroid market is expected to witness steady growth in the future. Owing to the rise in technological advancement, an increase in the number of chronic and cancer diseases and rise in healthcare expenditure are the key factors driving the growth of the market. In addition, the rising usage of organoid and spheroid culture systems for developmental biology further propels the growth of the market. However, the high cost of tissue culture and lack of awareness are expected to hamper the growth of the market to some extent over the forecast period.

On the contrary, the growing demand for 3D cell tissue culture technique to develop personalized medicines are expected to provide opportunities for the growth of the global organoids and spheroid market in the future.

Further, North America accounted for most of the organoids and spheroid market share in 2021 and is anticipated to remain dominant during the forecast period. Owing to the presence of several pharmaceutical and biotechnology companies that use 3D culture technology in collaboration with research institutes and clinical laboratories for developing regenerative medicines and drug discovery & development.

Asia-Pacific was the second largest contributor to the market in 2021 and is expected to register the fastest CAGR during the forecast period, due to economic development and low operating costs. Moreover, the rising focus on biopharmaceutical R&D, huge production of drugs, and surge in the prevalence of cancer are also propelling the growth of the market in this region

Author Name(s) : Vikita Thakur | Roshan Deshmukh

Related Tags

• Molecular Biology
• Stem Cell Research
• Clinical Trials
• Diagnostics