The global protein expression market was valued at $2,121 million in 2018 and is projected to reach $4,611 million by 2026, registering a CAGR of 10.2% from 2019 to 2026.
Protein expression refers to a biotechnological process of generating specific protein, typically attained by manipulation of gene expression in an organism such that it expresses large amounts of a recombinant gene. The development of genetic engineering and recombinant technologies has opened many possibilities of expression and isolation of heterologous proteins for research, clinical, and industrial purposes. Considerable advances in biotechnology have enabled expression and isolation of recombinant proteins in large scale. One of the major achievements is the development of recombinant proteins capable of entering a cell. Such developments lead to completely new opportunities in therapeutic medicine by targeting intracellular mechanisms or by substituting intracellularly operating enzymes though therapeutic protein. The first expression platform established was prokaryotic system through Escherichia coli. This was followed by development of other expression systems including yeast, algae, insect, and mammalian.
Protein expression finds major application in research, industrial and therapeutics and others. The therapeutic proteins such as peptide hormones, vaccines, monoclonal antibodies, therapeutic enzymes, antibodies, blood factors and cytokines are widely used to treat various chronic diseases such as cancer, diabetes, and multiple sclerosis. These proteins have elevated quality, accuracy and efficiency in biologics production.
The factors that boost the growth of the protein expression market include rise in geriatric population, age-related diseases and increase in prevalence of chronic diseases such as cancer. Moreover, increase in spending on protein research also fuel the growth of the protein expression market. However, high monetary inputs associated with the production of protein products restrict the growth of the market. In addition, significant shortage of trained healthcare professionals and lack of local expertise also restrains the market.
Improvements in innovations such as mass spectrometry, advancements in molecular genetics and advancement in manufacturing techniques are all key drivers on the protein therapy market. Furthermore, rapid developments in medical technology, better disease detection, and healthcare growth in emerging markets should have positive market impact.
Global Protein Expression Market Segmentation
The global protein expression market is segmented based on product, application, and region. Based on product, the market is bifurcated into reagents, expression vectors, competent cells, instruments, and services. By application, it is divided into therapeutic, industrial, and research. Based on region, it is analyzed across North America (U.S., Canada, and Mexico), Europe (Germany, the UK, Italy, Spain, France, and rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea, and, rest of Asia-Pacific) and LAMEA (Brazil, South Africa, Saudi Arabia, and rest of LAMEA). Some of the key players operating in the protein expression market include Agilent Technologies, Inc, Becton, Dickinson & Company, Bio Rad Laboratories, GenScript Biotech Corporation, LifeSensors Inc., Merck KGaA, Promega Corporation, QIAGEN N.V., Takara Holdings Inc. and Thermo Fisher Scientific Inc.
By Product
Competent cells is projected as one of the most lucrative segment.
Segment review
Based on product, protein expression market is bifurcated into reagents, expression vectors, competent cells, instruments and services. The reagents segment is expected to grow at a CAGR of 8.9% during the forecast period. The process of protein expression includes the use of reagents such as acids & bases, acrylamides, buffers, cell lysis of carbohydrates, detergents, general reagents, protease inhibitors and solvents. For research, industrial and pharmaceutical processing, these reagents have applications. It is therefore expected that repetitive buying of reagents for different applications will boost market growth.
The therapeutics segment was the highest contributor to the market in 2018, and the industrial and research segments are expected to witness significant CAGRs of 10.3% and 12.3%, respectively, during the forecast period.
By Application
Therapeutic market holds a dominant position in 2018 and would continue to maintain the lead over the forecast period.
Snapshot of region
Country wise, North America presents significant opportunities for the key players operating in the protein expression market, and Asia-Pacific is expected to witness significant CAGR of 11.2%, during the forecast period. This region offers lucrative opportunities for the protein market and is anticipated to register the highest growth rate during the forecast period. Moreover, increase in healthcare expenditure and surge in applications of protein expression is another major factor that boosts the growth of the market. In addition, presence of key players in these regions also fuels the growth of the protein expression in Asia-Pacific.
The key players profiled in this report include Agilent Technologies, Inc, Becton, Dickinson & Company, Bio Rad Laboratories, GenScript Biotech Corporation, LifeSensors Inc., Merck KGaA, Promega Corporation, QIAGEN N.V., Takara Holdings Inc. and Thermo Fisher Scientific Inc.
By Geography
Asia-Pacific region would exhibit the highest CAGR of 11.2% during 2019-2026.
Key Benefits for Stakeholders:
- The study provides an in-depth analysis of the protein expression market size along with the current trends and future estimations to elucidate the imminent investment pockets.
- It offers protein expression market analysis from 2019 to 2026, which is expected to enable the stakeholders to capitalize on the prevailing opportunities in the market.
- A comprehensive analysis on region assists to understand the regional market and facilitate the strategic business planning and determine prevailing opportunities.
- The profiles and growth strategies of the key players are thoroughly analyzed to understand the competitive outlook of the global protein expression market growth.
Protein Expression Market Report Highlights
| Aspects | Details |
 By Product |
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 By Application |
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 By Region |
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 Key Market Players | AGILENT TECHNOLOGIES, INC., LifeSensors Inc., Merck KGaA, Takara Holdings Inc., Promega Corporation, BECTON, DICKINSON AND COMPANY, QIAGEN N.V., THERMO FISHER SCIENTIFIC, INC., BIO-RAD LABORATORIES, INC., GenScript Biotech Corporation |
Analyst Review
Protein expression is defined as a biotechnological procedure, which includes generation of precise proteins. These proteins are formed through manipulation of gene expression in organisms of interest. The procedure leads to expression of large amounts of recombinant gene in organisms. Furthermore, this has led to many possibilities of expression and isolation of heterologous proteins for research, clinical, and industrial purposes. This, in turn, has led to advancements in genetic engineering and recombinant technologies. Significant advancements in the field of biotechnology have enabled expression and isolation of recombinant proteins on large scale. Some of products which are used to perform protein expression present in the market include reagents, expression vectors, competent cells, instruments, and others. These products are used in designing therapeutics and conducting research related to medicines.
According to CXOs of leading companies in the market, protein expressions are expected to witness high adoption in the future, owing to high requirement for protein research in novel drug designing for several chronic diseases such as cancer. Moreover, increase in spending on protein research also fuels the growth of the protein expression market. Moreover, rise in adoption of protein expressions is another factor that fuels the growth of the market. Asia-Pacific and LAMEA are expected to offer lucrative growth opportunities to the key players. This is majorly attributed to factors such as improvement in healthcare facilities, rise in disposable income, and rapid improvement in economic conditions. However, stringent regulations required for the production of protein drugs hinders the growth of the protein expression market. Protein Expression manufacturers and distributors have focused on expanding their presence in emerging economies to strengthen their foothold in the market.
The market value of global protein expression market was $2,121 million in 2018.
The forecast period is from 2019 to 2026.
The market value of global protein expression market in 2019 is $2,337 million.
Rise in geriatric population, increase in age-related and chronic diseases and increased spending on R&D expenditure fuel the growth of the market
The base year calculated in the report is 2018.
The services segments are growing at a rapid growth rate owing the increasing R&D expenditure from pharmaceutical and biotechnology companies and increasing application in therapeutics and research applications.
Rapid developments in medical technology, better disease detection, and healthcare growth in emerging markets should have positive market impact.
The North America market held a major share in the global protein expression market in 2018 and Asia-Pacific is fastest growing region in the forecasting period. This is attributed to increase in healthcare expenditure and surge in applications of protein expression is another major factor that boosts the growth of the market. In addition, presence of key players in these regions also fuels the growth of the protein expression in Asia-Pacific
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